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Figure 3 | Molecular Medicine

Figure 3

From: Insulin Decreases Inflammatory Signal Transcription Factor Expression in Primary Human Liver Cells after LPS Challenge

Figure 3

Dose response for LPS at various doses and various time points. We found that LPS causes a significant increase in IL-6 in the supernatant. We found that 100 µg/mL resulted in the greatest IL-6 increase 24 h after LPS administration. Similarly, the insulin dose response showed that insulin at 10 IU/mL demonstrated significant effects when hepatocytes were exposed to 100 µg/mL LPS. *Significant difference between controls and insulin 10 U/mL after LPS administration, P < 0.05.

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Molecular Medicine

ISSN: 1528-3658