Figure 5From: Insulin Decreases Inflammatory Signal Transcription Factor Expression in Primary Human Liver Cells after LPS ChallengeInsulin at a dose of 10 IU/mL significantly decreased the gene expression of hepatic TNF at 12 and 24 h, hepatic IL-1 β mRNA expression 12 h, hepatic IL-6 mRNA at 12 h, hepatic IL-10 mRNA at 8 and 12 h, and hepatic IFN-γ mRNA at 12 and 24 h after LPS administration. *Significant difference between LPS and LPS plus insulin, P < 0.05.Back to article page