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Figure 3 | Molecular Medicine

Figure 3

From: Genome-Level Longitudinal Expression of Signaling Pathways and Gene Networks in Pediatric Septic Shock

Figure 3

Comparison analysis of the signaling pathways corresponding to the 1,072 genes downregulated on day one and the 1,432 genes downregulated on day three of pediatric septic shock. The analysis is derived from the Ingenuity Pathways Analysis application (see text for details). The y-axis represents the -log (significance). For illustrative purposes, the x-axis crosses the y-axis at the 1.3 threshold of significance (i.e. -log (P value = 0.05) = 1.3). Significance is directly proportional to the number of genes within the data set that corresponds to the respective canonical signaling pathway, and inversely proportional to the number of genes in the entire data set uploaded to the Ingenuity Pathways Analysis application.

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