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Table 4 The Relationship of Risk Alleles and Haplotype of STAT4 with High CCP and RF Titer

From: Association of STAT4 with Rheumatoid Arthritis in the Korean Population

 

TTCG

Haplotype Others

P value

High antiCCPa

0.50

0.48

0.46

High RFa

0.42

0.39

0.33

RF titerb

   

Mean

219.9

181.9

0.29

Median

79.4

73.5

 

25 percentile

36.2

36.2

 

75 percentile

215.0

183.5

 
  1. aWe divided the cases into high or low anti-CCP/RF group based on the titer ≥ 100 units; Values indicate the frequency of cases with high anti-CCP or high RF out of given subjects; All risk alleles (data not shown) and haplotype do not affect the high anti-CCP or high RF titer frequency using chi square test [ORs (95% CI) 1.09 (0.86–1.38) and 1.11 (0.90–1.38) in order].
  2. bRF titer was not significantly related to risk haplotype using nonparametric statistics despite a trend toward higher titer in the risk groups.
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Molecular Medicine

ISSN: 1528-3658