Nonviral Vector Gene Modification of Stem Cells for Myocardial Repair

Table 6 Commercially available nonviral vector preparations.

Cationic polyplex vectors
	Polylysine vectors: poly-l-lysine, polylysine-molossin peptide, glycolysated polylysines, histidylated polylysine
	Polycation vectors: linear and branched polyethyleneimines (PEI, 70 Da to 800 kDa, ExGen500, JetPEI), poly(N-ethy-4-vinyl pyridinium bromide), polyamidoamine dendrimer (Superfect), poly(propylenimine) dendrimer (Astramol), Pluronic P123 (P123-g-PEI, 2k)
Cationic lipoplex vectors
	Cationic liposomal lipids: DOPE, DC-, DAC-, DCQ-, Sp-chol, BGTC, DOTMA, DOPE, DOSPA, DOTAP DMRIE, DOGS, DOSGA, DOSPER, DOCSPER, lipofectin (DOTMA + DOPE), lipofectamin, Lipofectamine2000, Superfect, Effectene, Tfx-50 Cationic non-liposomal lipids: FuGeneó
Combined lipopolyplex vectors
	lipofectamine + polylysine-molossin/DNA conjugates branched 25- or 50-kDa PEI + DC-Chol/DOPE liposomes

DOTMA, N-(l-(2,3-dioleoyloxy)propyl)-N,N,N-trimethylammonium; DOPE, dioleolyl phosphatidyl ethanolamine; DOSPA, 2,3-dioleoyloxy-N-(2-spermine carboxamide)ethyl-N,N-dimethyl-1-propanammonium trifluoroacetate; DOTAP, 1,2-bis(oleoyloxy)-3-(trimethylammonio)propane; DMRIE, N-(1-(2,3-dimyristyloxy)propyl)-N, N-dimethyl-N-(2-hydroxyethyl)ammonium bromide; DC-Chol, 3b-(N, N′, N′-dim-ethylaminoethane)carbamoyl)cholesterol; DOGS, transfectam (dioctadecyl aminoglyceryl spermine); DOSPER, 1,3-dioleoyloxy-2-(6-carboxy-spermyl)-propylamide.

ISSN: 1528-3658