Figure 1
(A) Effects of AM/AMBP-1 on acetylcholine (ACh)-induced vascular relaxation in aortic rings 20 h after cecal ligation and puncture (CLP). The data are expressed as percentage (%) of the vascular relaxation from the initial tension induced by 2×10−7 M norepinephrine. Values (n = 6/group) are presented as means ± SE and compared by one-way ANOVA and Tukey’s test: *P < 0.05 versus sham-operated animals; #P < 0.05 versus septic animals. (B) Effects of AM/AMBP-1 on nitroglycerine (NTG)-induced vascular relaxation in the aortic ring 20 h after cecal ligation and puncture (CLP). The data are expressed as percentage (%) of the vascular relaxation from the initial tension induced by 2×10−7 M norepinephrine. Values (n = 6/group) are presented as means ± SE. There was no significant difference between sham and septic animals with or without AM/AMBP-1 treatment.