Table 1 Collected series of heme oxygenase and liver IRI
From: Molecular Mediators of Liver Ischemia and Reperfusion Injury: A Brief Review
Reference | Model | Species | Modulating agent | Outcome |
|---|---|---|---|---|
Amersi et al. (65) | Cold IRI, OLT | Rat | CoPP, Ad-HO-1, ZnPP | Improved function with inducing agent |
Ito et al. (114) | Warm IRI | Rat | Doxorubicin, ZnPP | Improved function with inducing agent |
Kato et al. (66) | Cold IRI, OLT | Rat | CoPP, ZnPP | Improved function and survival with inducing agent |
Coito et al. (68) | Cold IRI, OLT | Rat | Ad-HO-1 | Improved function and survival |
Shen et al. (115) | Warm IRI | Mouse | CD154-CD40 T cell costimulation pathway | Improved function |
Redaelli et al. (116) | Cold IRI, OLT | Rat | CoPP, SnPP | Improved function and survival |
Amersi et al. (78) | Cold IRI | Rat | CO | Improved function |
Berberat et al. (117) | Cold IRI, OLT | Rat | Ad-H-ferritin | Cytoprotection and decreased IRI |
Ke et al. (118) | Cold IRI, OLT | Rat | Ad-IL-13, SnPP | Improved function |
Shen et al. (119) | Warm IRI | Mouse | Stat4-/-; SnPP | Decreased IRI |
Ke et al. (120) | Cold IRI, OLT | Rat | Ad-CD40 Ig | Improved function |
Fondevila et al. (74) | Cold IRI, OLT | Rat | Biliverdin | Improved function |
Shen et al. (121) | Warm IRI | Mouse | TLR4-/-, SnPP | Improved function |
Tsuchihashi et al. (67) | Warm IRI | Mouse | CoPP, ZnPP | Improved function |