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Figure 2 | Molecular Medicine

Figure 2

From: Pathogenic Autoantibodies in Systemic Lupus Erythematosus Are Derived from Both Self-Reactive and Non-Self-Reactive B Cells

Figure 2

Sequences of IgM anti-DNA antibodies. The sequences of the variable genes of three mutated antibodies were compared with their germline counterparts. The position of each mutated amino acid residue is indicated, with the germline encoded amino acid shown above the sequence. R/S represents the ratio of replacement to silent mutations. Underlined amino acids are within CDRs.

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Molecular Medicine

ISSN: 1528-3658