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Figure 4 | Molecular Medicine

Figure 4

From: Chronic Lymphocytic Leukemia Cells Recognize Conserved Epitopes Associated with Apoptosis and Oxidation

Figure 4

Hierarchical cluster analysis of autoantigen microarray reactivity of CLL mAbs. Results represent a two-dimensional cluster analysis in which CLL mAbs with similar binding patterns were assigned by computational algorithm to adjacent positions. In the second dimension, a similar computational clustering of antigenic reactivities is shown. Heat map: bright red represents highest relative antibody activity level; bright blue the absence of relative activity level. Results denote reactivity with antigens bound by ≥ 3 mAbs.

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