From: The Selective α7 Agonist GTS-21 Attenuates Cytokine Production in Human Whole Blood and Human Monocytes Activated by Ligands for TLR2, TLR3, TLR4, TLR9, and RAGE
LPS, ng/mL
GTS, µmol/L
NIC, µmol/L
% Cytotoxicity, mean ± SEM
P value
10
0
—
11.8 ± 2.07
1
13.7 ± 1.3
>0.05
11.9 ± 2.5
50
7.9 ± 1.8
100
11.6 ± 1.3
13.9 ± 1.1