| Â | ALL test groupb | Â | NORTH test group | SOUTH test group |
|---|
Marker seta | PC1 | PC2 | PC1 | PC2 | PC1 | PC2 |
|---|
Random 3,000 | 0.92c | 0.60 | 0.20 | 0.01 | 0.78 | 0.04 |
Random 6,000 | 0.96 | 0.77 | 0.55 | 0.05 | 0.93 | 0.36 |
Random 12,000 | 0.98 | 0.88 | 0.76 | 0.08 | 0.96 | 0.72 |
Random 24,000 | 0.99 | 0.95 | 0.88 | 0.37 | 0.98 | 0.87 |
Random 48,000 | 1.00 | 0.97 | 0.95 | 0.63 | 0.99 | 0.88 |
EUROset1 (2,795) | 0.95 | 0.79 | 0.54 | 0.01 | 0.92 | 0.45 |
EUROset2 (3,519) | 0.96 | 0.81 | 0.57 | 0.19 | 0.92 | 0.55 |
NORTHset1 (2,034) | NA | NA | 0.53 | 0.02 | NA | NA |
NORTHset2 (2,762) | NA | NA | 0.56 | 0.19 | NA | NA |
SOUTH (1,078) | NA | NA | NA | NA | 0.87 | 0.40 |
- aThe random marker results are the mean from three independently selected marker groups for each category (3K, 6K, 12K, 24K, and 48K). The EUROset2 contained EUROset1 markers. Similarly, the NORTHset2 contained the NORTHset1 SNPs. There was a small overlap of SNPs in the NORTH and SOUTH SNP set (see Materials and Methods and Supplemental Table 1 for details).
- bThe ALL test group included 789 European subjects and did not include any subjects used in AIMs selection (see Materials and Methods). The NORTH (378 subjects) and SOUTH (411 subjects) were subsets of the ALL test group determined from STRUCTURE results (see Materials and Methods).
- cAll correlations are shown as r2 values with PCA using 270,000 SNPs.
