High Incidence of MGMT and RARβ Promoter Methylation in Primary Glioblastomas: Association with Histopathological Characteristics, Inflammatory Mediators and Clinical Outcome

Table 2 Associations of MGMT, RARβ, RASSF1A, CDH13 promoter methylation with histopathological characteristics.

	MGMT methylation			RARβ methylation			RASSF1A methylation			CDH13 methylation
	Presence	Absence		Presence	Absence		Presence	Absence		Presence	Absence
	n	n	P	n	n	P	n	n	P	n	n	P
Necrosis			0.001			0.003			0.383			0.383
Absence	8	0		8	1		8	0		8	0
Focal	0	1		0	0		1	0		1	0
Diffuse	3	11		5	9		10	4		10	4
Histologic grade			0.005			0.019			0.539			0.539
II	6	0		6	0		6	0		6	0
IV	5	12		7	10		13	4		13	4

ISSN: 1528-3658