Figure 2
From: Factor VII Deficiency Impairs Cutaneous Wound Healing in Mice
Low FVII impairs reepithelialization and leukocyte migration during wound healing. (A–D) Immunohistochemical stains of d 5 wounds. Representative cytokeratin stains of wounded skin at d 5 postinjury in WT (A) and FVIItTA/tTA (B) mice. Original magnification 40×. The arrows indicate the distance from the edge of the wound (e) to the tip (t) of the keratinocytes. Representative CD45 stains (brown) at d 5 after wound induction in WT (C) and FVIItTA/tTA (D) mice. The orientation is marked with the location of the scar tissue (s) and hypodermis (h). Original magnification 200×.