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Table 1 Patients characteristics.

From: PPAR Signaling Pathway and Cancer-Related Proteins Are Involved in Celiac Disease-Associated Tissue Damage

Patient

Age/Sex

DQ2/8 variant

Modified MARSH grade

Celiac disease

Group

Diagnosis/diet (months)

Anti-Transglutaminasea

CD familiarity

    

CD patients

   

Patient 1

26/M

-b

0

Excluded

Group A

0/0

−/−

 

Patient 2

42/F

-

0

Excluded

Group A

0/0

−/−

 

Patient 3

16/F

DQ2

0

Excluded

Group A

0/0

−/−

 

Patient 4

19/F

-

0

Excluded

Group A

0/0

31/−

yes

Patient 5

59/F

DQ2

0

Excluded

Group A

0/0

31/−

 

Patient 6

25/M

-

0

Excluded

Group A

0/0

37/−

 

Patient 7

34/F

-

0

Excluded

Group A

0/0

52/−

 

Patient 8

44/M

DQ2

0

Suspectedc

Group A

36/36

−/−

 

Patient 9

46/M

DQ2

0

Suspectedd

Group A

0/0

−/7.5

 

Patient 10

39/F

DQ2

0

Confirmed

Group A

0/0

−/16

 

Patient 11

22/F

DQ2

0

Confirmed

Group A

0/0

−/73

yes

Patient 12

47/F

DQ2

I

Confirmed

Group A

60/58

−/−

 

Patient 13

34/M

DQ2

I

Confirmed

Group A

25/24

−/08

 

Patient 14

39/F

DQ2

II

Confirmed

Group B

0/0

26/16

 

Patient 15

52/M

DQ2

III A

Confirmed

Group B

0/0

−/15

 

Patient 16

36/M

DQ2

III B

Confirmed

Group B

0/0

26/20

 

Patient 17

41/M

DQ2

III B

Confirmed

Group B

0/0

−/21

 

Patient 18

38/F

DQ2

III A

Confirmed

Group B

0/0

130/NEe

 

Patient 19

33/F

DQ2

III A

Confirmed

Group B

0/0

336/NE

 
    

Refractory CD patients

   

Patient 20

32/F

DQ2

III B

Confirmed

 

96/72

−/−

yes

Patient 21

29/F

DQ8

III A

Confirmed

 

12/12

−/−

 

Patient 22

43/F

DQ2

III A

Confirmed

 

120/118

−/−

 

Patient 23

41/M

DQ2

III A

Confirmed

 

240/238

−/−

 

Patient 24

32/F

DQ2 and DQ8

III A

Confirmed

 

60/57

400/400

 
  1. aDashes indicate values lower than the cutoff.
  2. bDashes indicate patient does not carry either variant.
  3. cPatient with ulcerative jejunoileitis.
  4. dPatient with pancreatic cysts and intraductal tumor.
  5. eNE: not evaluated.