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Figure 6 | Molecular Medicine

Figure 6

From: Peripheral Administration of Human Adrenomedullin and Its Binding Protein Attenuates Stroke-Induced Apoptosis and Brain Injury in Rats

Figure 6

Effects of human AM/AMBP-1 on neutrophil infiltration in the brain after stroke. The figure shows immunohistochemical assessment of cerebral myeloperoxidase (MPO) at a coronal section at the bregma level from a sham-operated rat (Sham, A) and the penumbra area at a coronal section at the bregma level from stroke rats treated with human albumin (Vehicle, B), or human AM/AMBP-1 (AM/AMBP-1, C) at 24 h after permanent MCAO. Original magnification 200x. Scale bar = 50 µm. (D) Alterations in brain MPO activity in sham-operated animals (Sham) and stroke animals treated with human albumin (Vehicle) or human AM/AMBP-1 (AM/AMBP-1) at 24 h after permanent MCAO. Data are means ± SE (n = 4/group) and compared by one-way ANOVA and Student-Newman-Keul test: *P < 0.05 versus sham group; #P < 0.05 versus vehicle group.

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Molecular Medicine

ISSN: 1528-3658