Effects of Ad-ACE2 on Ang IIinduced cell proliferation (A, B) and type IV collagen production (C) in GMCs. Cell number was expressed as a percentage of the no treatment group. Type IV collagen contents were expressed as nanograms per milligram of cellular protein. *P < 0.05, #P < 0.01 versus no treatment group; ‡P < 0.05, §P < 0.01 versus Ad-GFP group. S, synthesis phase; G1, gap1; G2, gap2.