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Table 1 Biochemical and renal function measurements in six groups of rats.

From: Angiotensin-Converting Enzyme (ACE) 2 Overexpression Ameliorates Glomerular Injury in a Rat Model of Diabetic Nephropathy: A Comparison with ACE Inhibition

Parameters

Normal group (n = 10)

No treatment group (n = 10)

Ad-GFP group (n = 10)

Ad-ACE2 group (n = 10)

ACEI group (n = 10)

Ad-ACE2 + ACEI group (n = 10)

Blood glucose (mmol/L)

8.92 ± 0.48

28.94 ± 1.60

29.65 ± 1.42

29.07 ± 1.51

29.84 ± 1.61

29.70 ± 1.25

Body weight (g)

450.39 ± 9.36

259.65 ± 18.96b

261.43 ± 21.34b

295.56 ± 21.89a,c

287.24 ± 20.18a,c

286.60 ± 21.95a

KW/BW (g/kg)

3.41 ± 0.34

5.47 ± 0.46b

5.42 ± 0.51b

4.46 ± 0.42a,c

4.73 ± 0.37a,c

4.72 ± 0.31a,c

Urine volume (ml/24 h)

17.10 ± 1.57

140.19 ± 10.38b

133.86 ± 16.58b

62.68 ± 15.67a,c

58.33 ± 8.45a,c

53.91 ± 7.67a,c

  1. KW/BW, kidney weight-to-body weight ratio.
  2. aP < 0.05, bP < 0.01 versus normal group.
  3. cP < 0.05 for no treatment group.