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Table 2 HMGB1 levels in plasma and induced sputum of healthy subjects, noneosinophilic asthma patients and eosinophilic asthma patients.

From: High Mobility Group Protein Bl (HMGB1) in Asthma: Comparison of Patients with Chronic Obstructive Pulmonary Disease and Healthy Controls

Group

n

Plasma (ng/mL)

Induced sputum (ng/mL)

Control

34

3.71 (0.45–7.35)

0.41 (0–6.95)

Noneosinophilic asthma

20

6.30 (1.96–21.36)a

4.57 (1.05–14.68)b

Eosinophilic asthma

41

4.73 (1.18–15.74)a

3.80 (1.02–16.39)b

P

 

0.002

<0.001

  1. Data are medians (range).
  2. aP < 0.05 versus control group.
  3. bP < 0.001 versus control group.