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Figure 2 | Molecular Medicine

Figure 2

From: Validation of the Glaucoma Filtration Surgical Mouse Model for Antifibrotic Drug Evaluation

Figure 2

Increased number of eyes with intraoperative episcleral application of MMC maintained a lower IOP than control eyes. (A) The IOPs of both operated and unoperated eyes of each animal at the indicated postsurgery day were measured at least five times. Each value represents the % mean IOP of the operated eye over the mean IOP of the unoperated eye of the same animal at each time point measurements were taken. Each symbol represents a single animal (□, control, n = 8; ♦ MMC-treated, n = 8). The horizontal bars and numbers indicate the mean % IOP Dotted line indicates the 70% IOP level. C indicates control. (B) Graphical representation of the fraction of eyes with IOP maintained at less than 70% of the unoperated IOP of the same animal as a function of time after surgery. The values were calculated on the basis of panel A.

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