Figure 6
From: Validation of the Glaucoma Filtration Surgical Mouse Model for Antifibrotic Drug Evaluation
Cell death in the conjunctiva and episclera after MMC treatment. (A) Tissue sections were stained with Ki-67 (red) to visualize proliferating conjunctival epithelial cells in the control operated eye (arrowheads) versus the absence of any detectable proliferating cells in the MMC-treated operated eye; scale bar, 100 µm. (B) No apoptotic (TUNEL-positive) cells, which would have appeared as bright green cells, were seen in the control operated site, while many apoptotic cells were observed in the conjunctival epithelium as well as the episclera at the MMC-treated surgical site (arrowheads); scale bar, 10 µm.