Figure 2
From: Retroviral Insertional Mutagenesis Can Contribute to Immortalization of Mature T Lymphocytes
Marker profile. FACS analysis of the immortalized MP91-LMO2-transduced, mature T-cell population was performed after 6 wks of culture. (A) Over 90% of the cells expressed EGFP and the T-cell marker CD3. A loss in coreceptor (CD4 and CD8) expression, however, was observed (*). (B) The following mature T-cell markers were expressed: CD3, CD24 (low), TCR/β, Scal and CD25. No expression of the immature marker pre-TCR, however, was detected.