Figure 5

mTOR phosphorylation following RAPA treatment. The activation of the mammalian target of rapamycin (mTOR), as determined by ratios of phosphorylated mTOR to total mTOR measured by Western blot, are shown for diaphragm (Dia) (A) and tibialis anterior (TA) (B) muscles of systemic rapamycin (RAPA)-treated (Rapa H₂O) mdxmice and TA muscles of local RAPA-treated mdx mice (Rapa Bead) (C). n = 5 for RAPA-treated groups and n = 4 for untreated groups. **P < 0.01.