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Figure 5 | Molecular Medicine

Figure 5

From: PDZK1 Is a Novel Factor in Breast Cancer That Is Indirectly Regulated by Estrogen through IGF-1R and Promotes Estrogen-Mediated Growth

Figure 5

Correlation between PDZK1 upregulation and IGF-1R in breast cancer. (A) Correlation of PDZK1 protein expression with that of IGF-1R as assessed by immunohistochemistry by using TMA serial sections prepared from the same tissues where the Pearson correlation coefficient was r = 0.591 with p < 0.001. (B) Examples of PDZK1 in a positive or negative core with respective positive or negative expression of IGF-1R; insets represent a lower magnification but larger area of each sample. (C) Correlation between PDZK1 and IGF-1R transcripts (r= 0.537; p < 0.001) in breast cancer tissues determined using data deposited in the GEO Profiles database (14) and conducted by Boersma et al. (15).

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Molecular Medicine

ISSN: 1528-3658