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Figure 4 | Molecular Medicine

Figure 4

From: Kinase Activity Profiling of Gram-Negative Pneumonia

Figure 4

Validation of notable signals in the kinomics array. Western blots and quantifications were performed to validate notable signals in the kinomics chip. Western blots are shown in A and D; panels B, E, G and I contain graphs of densitometric assessment of Western blots Kinase activity data are represented in graphs C, F, H and J Phosphorylation patterns of p42 (A, B), p38 (D, E), SMAD1/5/8 (D, G) and SRC (D, I) based on Western blots match the kinase activity array data (C, F, H and J respectively). Array data are presented as a mean signal of two spots belonging to the kinase of interest Asterisks indicate significant events in kinomics profile. Data are mean ± SD of three mice per time point.

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