Figure 1
From: Brown Adipose Tissue Responds to Cold and Adrenergic Stimulation by Induction of FGF21
FGF21 mRNA levels are induced in BAT of wild-type C57BL/6J mice after exposure to cold for 4 h. (A) FGF21 mRNA levels were measured by quantitative RT-PCR in BAT, WAT and liver obtained from wild-type C57BL/6J mice. Bars show means ± SEM of eight mice per group. Data were analyzed by one-way ANOVA. Statistically significant differences between control mice and mice exposed to 4°C for the same tissue are shown (*P < 0.001). **Statistically significant differences between control tissues. (B) PPARα and PGC-1α mRNA levels were measured by quantitative RT-PCR in BAT of mice. Data were analyzed by a t test for each gene separately. *Statistically significant differences between control mice and mice exposed to 4°C.