|
AGE receptors
|
NSCLC cell line H358a (n= 3)
|
Lung tissuesb
|
P value
|
|---|
|
NSCLC (n = 89)
|
Control (n = 15)
|
|---|
|
Oligosaccharyl transferase-48 (OST-48, AGE-R1)
|
1,473 ± 105
|
775 (720–867)
|
658 (609–693)
|
<0.00001
|
|
80K-H phosphoprotein (AGE-R2)
|
3,295 ± 188
|
351 (316–391)
|
277 (257–314)
|
<0.00001
|
|
Galectin-3 (AGE-R3)
|
10,600 ± 1,366
|
1,209 (1),017–1,392)
|
1,103 (1),093–1,030)
|
0.138
|
|
Receptor for AGEs (RAGE)
|
84 ± 27
|
308 (226–445)
|
1,399 (1),201–1,639)
|
<0.00001
|
- aData of four independent experiments are given as mean ± SD.
- bMedian data are given with interquartile range and P values (NSCLC versus control lung) were calculated by use of the Student t test.
