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Table 2 mRNA expression of AGE receptors in human lung cancer.

From: Prognostic Potential and Tumor Growth-Inhibiting Effect of Plasma Advanced Glycation End Products in Non-Small Cell Lung Carcinoma

AGE receptors

NSCLC cell line H358a (n= 3)

Lung tissuesb

P value

NSCLC (n = 89)

Control (n = 15)

Oligosaccharyl transferase-48 (OST-48, AGE-R1)

1,473 ± 105

775 (720–867)

658 (609–693)

<0.00001

80K-H phosphoprotein (AGE-R2)

3,295 ± 188

351 (316–391)

277 (257–314)

<0.00001

Galectin-3 (AGE-R3)

10,600 ± 1,366

1,209 (1),017–1,392)

1,103 (1),093–1,030)

0.138

Receptor for AGEs (RAGE)

84 ± 27

308 (226–445)

1,399 (1),201–1,639)

<0.00001

  1. aData of four independent experiments are given as mean ± SD.
  2. bMedian data are given with interquartile range and P values (NSCLC versus control lung) were calculated by use of the Student t test.
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Molecular Medicine

ISSN: 1528-3658