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Figure 2 | Molecular Medicine

Figure 2

From: Macrophage Migration Inhibitory Factor Mediates Hypoxia-Induced Pulmonary Hypertension

Figure 2

Hypoxia-induced pulmonary vascular remodeling. Mice housed in a 10% normobaric oxygen atmosphere for 42 d demonstrated increased pulmonary vascular cell wall thickness. (A) histological sections from representative mice were immunostained with α-SMA (brown color) to reveal the muscular layer of the vessel wall. (B) Percentage wall thickness (WT%) was significantly increased in hypoxic mice. n = 10/group; **P < 0.01 versus normoxia.

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