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Figure 1 | Molecular Medicine

Figure 1

From: Altered Oxido-Reductive State in the Diabetic Heart: Loss of Cardioprotection due to Protein Disulfide Isomerase

Figure 1

PDI expression and cardiac cell death in nondiabetic and diabetic patients. (A-D) Bioptic myocardial tissue sections stained for PDI (A, B) and for TUNEL (C, D) to determine the ratio of PDI expression to cardiomyocyte cell death in nondiabetic (A, C) and diabetic (B, D) patients after myocardial ischemia. (E) Number of TUNEL-positive cells in samples with mild (+1), moderate (+2) and high expression of PDI. The values are expressed as percentage of TUNEL-positive cells per field on the total number of cardiomyocytes and are reported as interquartile ranges for both the groups of nondiabetic (n = 8) and diabetic (n = 7) patients.

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