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Figure 3 | Molecular Medicine

Figure 3

From: Human Skeletal Muscle Stem Cell Antiinflammatory Activity Ameliorates Clinical Outcome in Amyotrophic Lateral Sclerosis Models

Figure 3

Long-term monitoring of SPIO-labeled SkmSCs. (A, B) Representative MRI axial sections of T2-weighted images mouse brains (A) and T1-weighted images cervical spinal cord (B). (C) Photograph of Wr CNS. The immunostaining of Wr whole-mount spinal cord cervical region with anti-human nuclei (AHN) staining (mouse monoclonal antibody (mAb) anti-human nuclei; Chemicon, Temecula, CA, USA; 1:250) (red) 18 wks after transplant. All nuclei were counterstained with DAPI. T0 = MRI acquisition of pretransplanted mouse brain (4 wks of age); T1 = 0 h posttransplant (4 wks of age); T2 = 2 wks posttrans-plant (6 wks of age); T3 = 4 wks posttransplant (8 wks of age); T4 = 8 wks posttransplant (12 wks of age); T5 = 14 wks posttransplant (18 wks of age).

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Molecular Medicine

ISSN: 1528-3658