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Figure 1 | Molecular Medicine

Figure 1

From: Myeloid Angiogenic Cells Act as Alternative M2 Macrophages and Modulate Angiogenesis through Interleukin-8

Figure 1

MACs induce retinal microvascular network formation. (A) Green-labeled RMECs formed tubes in Matrigel. (B) Red-labeled MACs promoted RMEC tube formation. Scale bars: 500 µm. (C) Higher magnification of coculture showing red-labeled MACs did not incorporate into the vascular network. Scale bar: 200 μm. (D) Quantification of tube length. (D) Quantification of tube area. (E) Addition of MAC-CM significantly increased RMEC tube formation as measured by tube length when compared with nonconditioned media. Data expressed as mean ± SEM. ***P < 0.001 versus control; *P < 0.05 versus control.

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