Figure 1

TF deficiency reduces the severity of clinical indices of DSS colitis in mice. (A) TFlow mice fed 1.5% (w/v) DSS in their drinking water for 7 d were protected against body weight loss compared with wild-type mice. The TFlow mice presented smaller changes in colon length (B) and colon weight (C) (shown in mg/cm) than wild-type mice. Data are means ± SEM (n = 7). *P < 0.05, **P < 0.01, ***P < 0.001.