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Table 3 Association between CALHM1 P86L genotype (rs2986017) and CSF Aβ levels in the cognitively healthy cohort.a

From: CALHM1 P86L Polymorphism Modulates CSF Aβ Levels in Cognitively Healthy Individuals at Risk for Alzheimer’s Disease

Genetic transmission model

Aβ1–40

Aβ1–42

Dominant

P= 0.1656

P= 0.0099

Additive

P= 0.0237

P= 0.0036

Recessive

P= 0.0123

P= 0.0669

  1. aAdjusted for APOE genotype, age of the patient at CSF collection time, gender, and BACE1 levels.
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Molecular Medicine

ISSN: 1528-3658