|
Gene
|
Differentiated
|
RSVA314
|
RSVA405
|
|---|
|
Ceacam1
|
3.04 ± 0.37a
|
0.60 ± 0.12b
|
0.81 ± 0.26b
|
|
Trib3
|
0.08 ± 0.03a
|
0.72 ± 0.14b
|
0.69 ± 0.08b
|
|
PPARg
|
1.57 ± 0.05c
|
0.72 ± 0.04b
|
0.67 ± 0.06b
|
|
Agt
|
5.46 ± 2.17c
|
0.36 ± 0.17b
|
0.36 ± 0.12b
|
|
Pik3r1
|
1.59 ± 0.12c
|
0.87 ± 0.07b
|
0.84 ± 0.06b
|
|
Cebpa
|
2.79 ± 0.21c
|
0.70 ± 0.07d
|
0.74 ± 0.06d
|
|
Retn (resistin)
|
4.95 ± 0.45c
|
1.12 ± 0.05d
|
1.24 ± 0.22d
|
|
Slc2a4 (GLUT4)
|
11.20 ± 7.41c
|
2.48 ± 1.55d
|
1.47 ± 0.28d
|
|
Snap25
|
4.94 ± 1.23c
|
1.11 ± 0.04d
|
1.23 ± 0.21d
|
|
Srebf1
|
1.79 ± 0.04c
|
0.96 ± 0.08d
|
0.91 ± 0.05d
|
|
Foxc2
|
1.94 ± 0.06c
|
1.13 ± 0.16d
|
1.13 ± 0.10d
|
|
Ccl5 (RANTES)
|
0.54 ± 0.07e
|
1.12 ± 0.17b
|
1.74 ± 0.20b
|
|
Gpd1
|
1.67 ± 0.31e
|
0.78 ± 0.16b
|
0.39 ± 0.18b
|
|
Vamp2
|
0.76 ± 0.09e
|
1.42 ± 0.13b
|
1.18 ± 0.19d
|
|
Pfkfb3
|
2.45 ± 0.91e
|
1.04 ± 0.51d
|
1.33 ± 0.45d
|
|
II4ra
|
1.53 ± 0.01e
|
1.03 ± 0.07f
|
0.75 ± 0.09d
|
|
Igfbp5
|
3.73 ± 0.87e
|
1.12 ± 0.05f
|
1.24 ± 0.22f
|
|
Nrf1
|
0.73 ± 0.05e
|
0.97 ± 0.03f
|
0.96 ± 0.03f
|
|
Ace
|
2.49 ± 0.46e
|
1.87 ± 0.51
|
1.24 ± 0.22f
|
|
Icam1
|
0.31 ± 0.13
|
2.03 ± 0.51
|
2.23 ± 0.35f
|
- Gene expression was analyzed by real-time PCR using RNA from 3T3-L1 cells differentiated for 2 d and treated or not with the RSVAs (2 μmol/L). Data are expressed as fold-change compared with nondifferentiated control condition ± standard deviation (SD) of three independent experiments.
- aP < 0.001, cP < 0.01, eP < 0.05, versus nondifferentiated condition.
- bP < 0.001, dP < 0.01, fP < 0.05, versus differentiated condition (Student ttest).
