Week(s) of treatment | Standard diet | HFD | HFD + RSVA405 (20 mg/kg/d) | HFD + RSVA405 (100 mg/kg/d) |
---|---|---|---|---|
1 | 20 ± 1.6 | 18.2 ± 0.9 | 18.4 ± 1.1 | 18.5 ± 1.1 |
2 | 22.2 ± 1.8 | 23 ± 0.7 | 22 ± 1 | 22.3 ± 1 |
3 | 23.4 ± 1.8 | 27.3 ± 0.5a | 24.3 ± 1.36b | 24.6 ± 1.4c |
4 | 24.5 ± 2.4 | 29 ± 0.4a | 27.1 ± 2.2c | 25.9 ± 1.9c |
5 | 25.8 ± 2.9 | 31.4 ± 0.8a | 30.2 ± 2.2 | 28.4 ± 1.9c |
6 | 27.6 ± 3.5 | 34.7 ± 1.1d | 33 ± 2.3c | 30.4 ± 2.1c |
7 | 28.4 ± 3.2 | 37.2 ± 1.1d | 34.8 ± 3.1c | 32.8 ± 2.2c |
8 | 28.7 ± 3.2 | 40.7 ± 1.4e | 36.4 ± 2.3c | 35.4 ± 2.3c |
9 | 29.7 ± 3.2 | 42.8 ± 1.6e | 38.4 ± 2.3c | 36.8 ± 2.6b |
10 | 31 ± 3.2 | 45.2 ± 1.4e | 39.9 ± 2.5c | 38.6 ± 2.6b |
11 | 32.4 ± 3.2 | 46.5 ± 1.2e | 42 ± 2.4c | 40.8 ± 3c |