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Table 3 Effect of RSVA405 administration on fasted blood glucose, triglycerides and cholesterol at the end of the treatment period in mice fed an HFD.

From: Small-Molecule Activators of AMP-Activated Protein Kinase (AMPK), RSVA314 and RSVA405, Inhibit Adipogenesis

 

Standard diet

HFD

HFD + RSVA405 (20 mg/kg/d)

HFD + RSVA405 (100 mg/kg/d)

Glucose (mg/dL)

199 ± 31

238 ± 30

204 ± 56

187 ± 29

Triglycerides (mg/dL)

101 ± 5

90 ± 8

117 ± 10

130 ± 26

Cholesterol (mg/dL)

138 ± 77

291 ± 34

295 ± 22

276 ± 23

  1. Data are mean ± SD. n = 5.