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Table 3 Effect of RSVA405 administration on fasted blood glucose, triglycerides and cholesterol at the end of the treatment period in mice fed an HFD.

From: Small-Molecule Activators of AMP-Activated Protein Kinase (AMPK), RSVA314 and RSVA405, Inhibit Adipogenesis

  Standard diet HFD HFD + RSVA405 (20 mg/kg/d) HFD + RSVA405 (100 mg/kg/d)
Glucose (mg/dL) 199 ± 31 238 ± 30 204 ± 56 187 ± 29
Triglycerides (mg/dL) 101 ± 5 90 ± 8 117 ± 10 130 ± 26
Cholesterol (mg/dL) 138 ± 77 291 ± 34 295 ± 22 276 ± 23
  1. Data are mean ± SD. n = 5.