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Figure 1 | Molecular Medicine

Figure 1

From: Interstitial Lung Disease and Pulmonary Fibrosis in Hermansky-Pudlak Syndrome Type 2, an Adaptor Protein-3 Complex Disease

Figure 1

Representative transmission electron micrographs from a subject with HPS-2 and severe interstitial lung disease. (A) and (B) show hyperplasia of type II cells (solid large arrows) with lamellar bodies (open large arrows) in the alveolar interstitial space from subject 1. Some type II cells have acicular spaces (small arrows) in the cytoplasm. Myofibroblasts (*) and collagen fiber bundles (C) are identified in the alveolar interstitium (C). Some areas of the lung contain capillaries with regional thickening of the basement membrane (arrowhead) (D).

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