Table 2 TdT and exonuclease activity in productively rearranged IGHD-IGHJ (D-J) versus IGHV-IGHD-IGHJ (V-D-J) in CLL and ALL.

TdT activity

Positivity (%)

96.9

92.0

90.0

89.8

0.03

0.92

0.01

Median number of nucleotides (range)

9 (1–76)

7 (1–39)

8 (1–34)

6 (1–81)

0.01

0.96

0.13

3′ IGHD exonuclease activity Positivity (%)

87.6

81.8

88.5

85.7

0.06

0.98

0.52

Median number of nucleotides (range)

4 (1–24)

4 (1–19)

4 (1–25)

5 (1–16)

0.74

0.12

0.26

5′ IGHJ exonuclease activity Positivity (%)

86.6

86.6

85.4

77.6

0.99

0.08

0.84

Median number of nucleotides (range)

5 (1–27)

5 (1–29)

6 (1–25)

5 (1–16)

0.39

0.06

0.06