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Figure 2 | Molecular Medicine

Figure 2

From: Microglial Stimulation of Glioblastoma Invasion Involves Epidermal Growth Factor Receptor (EGFR) and Colony Stimulating Factor 1 Receptor (CSF-1R) Signaling

Figure 2

Iressa blocks microglia-stimulated glioblastoma invasion but not growth. (A) Invasion of GL261 cells plated with additional GL261 (open bar), microglia (closed bar; + MG) or microglia in the presence of 5 µmol/L Iressa (closed bar; + MG, Iressa). Means ± SEM of three independent experiments. *P < 0.05 + MG versus + MG Iressa. (B, C) SRB assay showing growth of either GL261 (B) or microglia (C) cultured under invasion assay conditions in DMSO (open bars) or 5 µmol/L Iressa (closed bars). Results are normalized to the day of drug addition. Means ± SEM from three independent experiments. A.U., arbitrary units.

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