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Figure 11 | Molecular Medicine

Figure 11

From: Identification of ING4 (Inhibitor of Growth 4) as a Modulator of Docetaxel Sensitivity in Human Lung Adenocarcinoma

Figure 11

ING4 expression was downregulated in DTX nonresponding tumors from lung adenocarcinoma patients. (A) Immunostaining of ING4 protein in lung adenocarcinoma tissues. Positive ING4 protein staining was mainly located in the nucleus of tumor cells. a, negative staining (20×); b, negative staining (100×); c, positive staining (20×); d, positive staining (100×). (B) Scores of ING4 immunostaining in lung adenocarcinoma tissues. Tumor tissues were obtained from 8 responding and 10 nonresponding patients. (C) Statistical analysis of PFS of lung adenocarcinoma patients according to the level of ING4 protein expression in tumor tissues. The p value was determined with the log-rank test. Scale bars: 160 µm (a, c); 400 µm (b, d).

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