Effect of ING4 overexpression on apoptosis and cell cycle of SPC-A1/DTX or A549/Taxol cells. (A) Flow cytometric analysis of cell cycle in SPC-A1/DTX/ING4 (or SCP-A1/DTX/control) and A549/Taxol/ING4 (or A549/Taxol/control) cells. (B) Flow cytometric analysis of apoptosis in SPC-A1/DTX/ING4 (or SPC-A1/DTX/control) and A549/Taxol/ING4 (or A549/Taxol/control) cells. Results represent the average of three independent experiments (mean ± SD). *p < 0.05 and **p < 0.01 compared with SPC-A1/DTX/control or A549/Taxol/control cell line.