Skip to main content

Table 1 Differentially expressed genes with a >15.0-fold change in the DTX-resistant SPC-A1 cell line (SPC-A1/DTX) compared with the parental SPC-A1 cell line.

From: Identification of ING4 (Inhibitor of Growth 4) as a Modulator of Docetaxel Sensitivity in Human Lung Adenocarcinoma

cDNA expression profiles
Upregulated in SPC-A1/DTX Downregulated in SPC-A1/DTX
Gene symbol Fold changea P b Gene symbol Fold changea P b
PDE1A 99.7 0.003 SERPINB5 60.9 < 0.001
SLC7A7 83.9 0.012 LUM 57.3 0.007
ALDH2 49.9 0.005 ING4 39.4 0.001
BIRC7 41.1 0.004 CYP1A1 33.8 0.003
TESCALCIN 37.5 0.021 RASIP1 24.5 0.006
MUC13 37.5 0.006 RNASEK 22.1 0.011
NOTCH1 34.5 < 0.001 TMPRSS11F 20.4 <0.001
CHST13 34.3 0.009 GALR2 18.7 0.006
STMN3 31.8 <0.001 KRT15 18.5 <0.001
KLHDC9 30.7 0.014 RUNX3 17.8 0.009
UBE2L6 30.5 0.001 ABCG 2 17.1 0.001
OLFM1 29.7 0.001 ABCC 3 16.5 0.006
FNDC5 22.8 0.003    
PTGDS 21.9 0.005    
CTSH 21.0 <0.001    
TCAM1P 20.7 0.018    
NAP1L5 18.5 0.007    
FAM18A 18.5 0.004    
KIR2DL1 17.5 0.002    
  1. aFold change values were generated from the median expression of the miRNAs in the groups compared.
  2. bStudent t test p values.