Figure 3From: Interferon Regulatory Factor-1 Regulates the Autophagic Response in LPS-Stimulated Macrophages through Nitric OxidePeritoneal macrophages from IRF-1 KO mice demonstrate decreased apoptosis in response to LPS stimulation. Peritoneal macrophages were isolated from WT and KO mice and were treated with/without LPS (1 µg/mL) stimulation for 16 h or 32h and were analyzed by (A) TUNEL staining or (B) cleaved caspase-3 by Western blot. *,#P < 0.05; results representative of three separate independent experiments.Back to article page