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Table 1 Results of immunohistochemical staining of DEPTOR expression in tumorous (T) versus tumor-adjacent (TA) tissues from 51 HCC patients and the associations with their clinical and pathological characteristics.

From: Functional Characterization of Glycine N-Methyltransferase and Its Interactive Protein DEPDC6/DEPTOR in Hepatocellular Carcinoma

 

DEPTOR expression (n (%))

  

Characteristic

T < TA

T = TA

T > TA

All (%)

P

Patients (n)

6 (11.8)

31 (60.8)

14 (27.5)

51

 

Age (years), mean ± SD

58.7 ± 18.0

60.0 ± 12.4

60.6 ± 15.0

60.0 ± 13.5

 

Sex

    

0.186

Female

3 (11.5)

18 (50.0)

4 (38.5)

26 (100)

 

Male

3 (12.0)

13 (72.0)

10 (16.0)

25 (100)

 

Cirrhosis

    

0.272

Negative

4 (12.9)

21 (67.7)

6 (19.4)

30 (100)

 

Positive

2 (10.0)

11 (50.0)

8 (40.0)

21 (100)

 

Viral infectiona

    

0.020

NBNC

5 (29.4)

11 (64.7)

1 (5.9)

17 (100)

 

HBV

0 (0.0)

9 (56.2)

7 (43.8)

16 (100)

 

HCV

1 (5.6)

11 (61.1)

6 (33.3)

18 (100)

 

Tumor type

    

0.236

Solitary

3 (8.3)

21 (58.3)

12 (33.4)

36 (100)

 

Multiple

3 (20.0)

10 (66.7)

2 (13.3)

15 (100)

 

Vascular invasion

    

0.328

Absent

1 (4.3)

15 (65.2)

7 (30.5)

23 (100)

 

Vein invasion or vein tumor thrombosis

5 (17.9)

16 (57.1)

7 (25.0)

28 (100)

 

TNM stageb (AJCC and UICC, 7th

     

edition (46))

    

0.088

Early

0 (0.0)

14 (66.7)

7 (33.3)

21 (100)

 

Late

6 (20.0)

17 (56.7)

7 (23.3)

30 (100)

 
  1. aHBV, HBV sAg (+); HCV, anti-HCV antibody (+); NBNC, HBV sAg (−) and anti-HCV antibodies (−).
  2. bEarly stage, TNM stage = I; late stage, beyond TNM stage I (TNM stage = II + IIIA + IIIB + IIIC + IV).