Heatmaps illustrating genes typically expressed differentially between the proliferative versus resting fractions of CLL clones. (A) Pro- and antiproliferation genes up- or downregulated in the proliferative versus resting fractions of the nine CLL clones analyzed. (B) Antiapoptotic genes. (C) Genes related to oxidative injury. (D) Trafficking-related genes. (A-D) Genes presented are significantly differentially expressed (Supplementary Table 1) and were assigned to categories using Ingenuity Pathway Analysis, Panther Classification System, DAVID Bioinformatics Resources 6.7 and GeneCards Batch Queries. Significantly differentially expressed gene expression values for each set were clustered using hierarchical clustering on the basis of the average linkage on a correlation-based distance.