ApoE−/− GNMT−/− mice show exacerbated inflammatory response. A and B) ELISA analysis of serum levels of IL-6, TNF-α, MCP-1 and MIP-2 in serum and aortas of apoE−/− mice and apoE−/− GNMT−/− mice. C, Western blot analysis and quantitation of VCAM-1, inducible iNOS, phosphorylated eNOS (p-eNOS) and eNOS in aortic lysates from apoE−/− and apoE−/− GNMT−/− mice. α-Tubulin was a loading control. Data are mean ± SEM from 14 animals. *P > 0.05 versus apoE−/− mice.