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Figure 3 | Molecular Medicine

Figure 3

From: Effect of Nuclear Factor κB Inhibition on Serotype 9 Adeno-Associated Viral (AAV9) Minidystrophin Gene Transfer to the mdx Mouse

Figure 3

Quantification of human minidystrophin expression in quadriceps, heart and diaphragm muscles. Minidystrophin transgene protein expression was detected from total protein extracts by Western blot analysis. (A) Three representative bands reflecting the range of results are shown for quadriceps, heart and diaphragm muscles. There is no human minidystrophin expression in quadriceps, heart and diaphragm in mdx and C57BL/10 controls (data not shown). (B) Densitometric quantification of bands from all mice in each group was normalized to GAPDH expression. All quantitative data are shown as mean ± SEM.; *significant difference from AAV + saline-treated mdx mice (P < 0.05); n = number of animals analyzed.

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Molecular Medicine

ISSN: 1528-3658