Figure 4From: Effect of Nuclear Factor κB Inhibition on Serotype 9 Adeno-Associated Viral (AAV9) Minidystrophin Gene Transfer to the mdx MouseActivation of NF-κB. (A) NF-κB activation was analyzed by electrophoretic mobility shift assay of nuclear protein extracts of diaphragm and quadriceps muscle tissue in age-matched, untreated C57BL/10 and mdx mice and AAV + NBD peptide- and AAV + saline-treated mdx mice. Three representative bands reflecting the range of results are shown. (B) Densitometric quantification of bands from all treated and control mice were averaged and are presented as mean ± SEM. *Significant difference from untreated mdx mice (P < 0.05); n = number of animals analyzed.Back to article page