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Figure 4 | Molecular Medicine

Figure 4

From: Axitinib Targeted Cancer Stemlike Cells to Enhance Efficacy of Chemotherapeutic Drugs via Inhibiting the Drug Transport Function of ABCG2

Figure 4

Effect of axitinib on the ATPase activity of ABCG2. The vanadate-sensitive ATPase activity of ABCG2 was determined at different concentrations of axitinib. The inset shows the effect of lower concentrations of axitinib on ABCG2ATPase activity. ATP hydrolysis was monitored by measuring the amount of inorganic phosphate released using a colorimetric assay.

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