Figure 1From: Pharmacological Rescue of the Mutant Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Detected by Use of a Novel Fluorescence PlatformTopology of CFTR with FAP reporters. (A) Schematic diagram of CFTR tagged with a FAP reporter at the N-terminus via an extra transmembrane spanning fragment (FAP-CFTR). (B) Insertion of the FAP in the fourth extracellular loop of CFTR located between the two glycosylation sites (CFTR EL4-FAP).Back to article page