Figure 1From: Mammalian DNA Is an Endogenous Danger Signal That Stimulates Local Synthesis and Release of Complement Factor BFactor B is not upregulated in macrophages by common known TLR4-mediated DAMPs. Expression of factor B mRNA in RAW264.7 macrophages treated with LPS (positive control), or DAMPs (fibrinogen, heparan sulfate, HMGB1) or PBS (control) for 6 h. *p < 0.05 versus control. Experiment performed in triplicate and repeated at least three times.Back to article page